Nontraditional risk factors shed light on unexplained strokes in adults younger than 50

Among adults ages 18-49 (median age of 41 years) who were born with a hole in the upper chambers of their heart known as patent foramen ovale (PFO), strokes of unknown cause were more strongly associated with nontraditional risk factors, such as migraines, liver disease or cancer, rather than more typical factors such as high blood pressure.  

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